Person cleaning a home surface with a pet nearby, illustrating how topical probiotics work for both pet care and everyday cleaning

How do probiotics work?

How probiotics work on skin and surfaces

Topical probiotics work by supporting microbial balance on skin, surfaces, and in the environment. Instead of relying on harsh chemicals or antibacterial agents, they work through natural biological processes that support beneficial microbes. This helps create conditions that are healthier, more stable, and longer-lasting.

This page explains how probiotics work beyond the gut, how topical probiotic sprays work on skin and surfaces, and why this balance-based approach differs from traditional cleaning and pet care methods.


Person gently cleaning a dog’s eye with a cotton pad, showing how topical probiotics work for everyday pet eye care

The microbiome: a living ecosystem

Every surface you interact with has its own microbiome - a community of microscopic organisms such as bacteria and fungi that naturally live there. This includes your pet’s skin, coat, ears, eyes and teeth, the floors and surfaces in your home, and even the air you breathe indoors.

A healthy microbiome isn’t meant to be sterile - it works best when it is balanced. However, if this balance becomes disrupted, unwanted microbes can start to gain the upper hand. You may notice this as skin irritation, odours, bad breath, yeast overgrowth, increased sensitivity, or spaces that feel less comfortable for people and pets.

This is where how probiotics work becomes important: topical probiotics support the microbiome by helping to maintain that natural balance.

What makes topical probiotics different?

Although bacteria are often associated with illness, not all bacteria are harmful. In fact, the helpful ones (probiotics) play an important role in:

  • breaking down organic matter
  • supporting natural defences
  • limiting the growth of more problematic microbes

However, traditional cleaning and pet care products often work by removing or killing microorganisms - both harmful and helpful. Although this can deliver short-term results, it may also disrupt the wider microbial ecosystem, known as the microbiome, both locally and beyond.

In contrast, probiotic products take a different approach. How probiotics work differently is by introducing beneficial bacteria directly and supporting balance over time through two natural biological processes: bio-competition and bio-augmentation.

In simple terms:

  • they don’t try to wipe everything out
  • they help the right microbes take the lead.

How topical probiotics work - the core mechanism

To understand how probiotics work on skin and surfaces, it helps to look at the two biological processes they use to support microbial balance.

Illustration of friendly probiotic bacteria showing how probiotics work through microbial competition

1. Bio-competition - holding the line

All microorganisms need space, nutrients, and time to survive and thrive. When beneficial probiotic bacteria are introduced in sufficient numbers - such as through probiotic products - they compete successfully for these resources.

This is a key part of how probiotics work: by naturally occupying space and nutrients first, they limit the ability of less helpful microbes to establish themselves.

In simple terms, probiotics hold the line. They act like a protective, friendly home guard, naturally occupying space and resources and leaving fewer opportunities for unwanted microbes - including harmful bacteria - to gain a foothold.

Diagram comparing traditional cleaning and probiotic cleaning, showing how probiotics work to support microbial balance

2. Bio-augmentation - balance over time

Once beneficial bacteria (the probiotics) hold that space, the next stage of how topical probiotics work begins.

With repeated application, they become established and help restore a healthier ratio between helpful and less helpful microbes within the microbiome. Over time, they simply tip the balance back in favour of helpful microbes - rather than wiping out the existing microbial community.

For example, on skin or surfaces, they help create conditions where helpful microbes can thrive and less helpful ones - such as those linked with odours or irritation - struggle to take hold.

As organic residues such as pollen, dust mite allergens, and odour molecules break down, the microbial community grows more balanced and resilient over time.

Instead of repeatedly stripping the microbial environment back and forcing it to reset, this is how probiotics work to support a healthier, self-regulating ecosystem.

These processes of bio-competition and bio-augmentation are biological and mechanical, not chemical. This is why topical probiotics are suitable for routine, everyday use - quietly maintaining balance in the background, long after application.

Diagram illustrating how probiotics produce enzymes to break down organic matter

Enzyme activity – breaking down organic matter naturally

A key part of bio-augmentation also involves enzyme production.

Enzymes are specialised proteins produced by living cells, including bacteria. They act as natural catalysts, helping to speed up specific biological reactions.

In cleaning and on skin, this means helping to break down complex organic substances into simpler components. For example, organic residues such as oils, fats, proteins, carbohydrates, sweat, sebum, pollen, food particles, and odour-causing compounds can be broken down through enzymatic processes.

Enzymes are highly specific. Each type of enzyme supports a particular reaction. In many conventional cleaning formulations, one or more isolated enzymes are added to target specific types of dirt.

Probiotic bacteria, however, are living microorganisms. A single probiotic bacterium is capable of producing a wide range of different enzymes. In fact, bacterial DNA contains the instructions to produce many thousands of enzyme types.

This means that, as probiotics establish themselves on a surface or on skin, they can produce enzymes in response to the organic material present. Rather than relying on a fixed set of added enzymes, the bacteria themselves generate the enzymes needed to help break down the residues available.

In simple terms, enzymes help “cut” complex organic matter into smaller components. The probiotic bacteria can then continue to process these substances as part of the wider microbial ecosystem.

This combined activity helps explain how probiotics work beyond immediate surface cleaning. Instead of delivering only a short-term effect, they support ongoing biological processes that contribute to longer-lasting balance.

Together, bio-competition, bio-augmentation, and enzyme activity explain how probiotics work naturally to support microbial balance over time.

Learn more about the difference between probiotic and enzyme cleaning →

Clean kitchen surface with probiotic spray showing how probiotics work over time to support microbial balance

Why probiotics keep working after application

One of the clearest examples of how probiotics work differently from conventional products is what happens after the surface dries.

The issue with many traditional products is that they deliver an immediate effect, but stop working once you rinse them away or they evaporate.

Topical probiotics, by contrast, remain present as part of the microbial ecosystem. Once applied, they continue to function for up to 72 hours between applications, helping to:

  • break down organic matter
  • maintain a more stable balance between applications
  • support longer-lasting freshness

This ongoing activity is why people often describe probiotic cleaning and care as working with the environment, rather than acting on it temporarily. Probiotic care continues working quietly in the background - even once surfaces are dry.

How this differs from antibacterial approaches

Antibacterial products act broadly, reducing many types of microorganisms without distinguishing between helpful and harmful ones. Although this can be useful in certain situations, frequent use can disrupt microbial balance and encourage the survival of only the most resilient microbes.

Topical probiotics take a different route. How probiotics work here is by introducing beneficial bacteria to support a more diverse and balanced microbial environment. In practice, this means they:

  • support diversity rather than sterility
  • focus on balance, not blanket elimination
  • work without contributing to antimicrobial resistance (AMR), where microbes adapt to repeated exposure to antimicrobial products over time, making them harder to control

This balance-focused approach aligns with growing awareness around antimicrobial stewardship - using antibiotics and antimicrobial products carefully, and only where they’re truly needed.

This wider shift towards working with natural systems, rather than relying solely on continual microbial eradication, is increasingly reflected in international guidance. Organisations such as the World Health Organization have highlighted the importance of reducing unnecessary antimicrobial pressure in everyday environments.

This is particularly relevant for everyday pet and home care, where long-term balance often matters more than short-term eradication.

Relaxed cat in a calm home environment, illustrating cleanliness and balance

What this means for everyday use

Because topical probiotics work naturally - through biological processes rather than chemical action - they are supportive rather than aggressive. They help maintain healthier conditions over time, instead of relying on repeated environmental “resetting”.

They are well suited to:

  • regular pet care routines, including dental and coat care
  • everyday home and workplace cleaning
  • environments where people and animals spend a lot of time.

Want to explore where topical probiotics are used?

If you’d like to see how this science is applied in everyday life, explore how topical probiotics support practical applications:

Or, if you’d like to start with the foundations, you can explore the basics:

If you have questions or would like help choosing the right products, our team is always happy to guide you.